Institute of Macromolecular Chemistry, Academy of Sciences


Phone : +420-296809260

Email : horak a(t)

COST ROLE : Member

Daniel Horák (Czech Republic)

Description of the Organisations and PI

Institute of Macromolecular Chemistry, AS CR, established in 1962, pursues basic, target-oriented, and applied research in chemistry and physics in polymers. The Institute has a total staff 250 people and the research is conducted at 10 scientific departments. The Department of Polymer Particles is involved in synthesis, characterisation, functionalisation and biomedical application of magnetic and upconversion polymer nano- and microspheres based on synthetic and natural polymers. Recently, monodisperse particles were developed with controlled size, porosity, swelling behaviour and magnetic and upconversion properties.

Daniel Horák received his PhD in macromolecular chemistry, is the head of the Department of Polymer Particles. His research activity is focused on the design, characterisation and application of magnetic and upconversion polymer nano- and microspheres, heterogeneous polymerisation systems (emulsion, suspension and dispersion polymerisation), properties of the particles, their chemical modifications and applications in medicine, biochemistry and biotechnology, immobilisation of enzymes and antibodies. He has published more than 200 original scientific papers, several book chapters (Polymeric Materials Encyclopedia, Strategies in Size Exclusion Chromatography, Citus Books, etc.), and 7 patents. He is a member of International Polymer Colloid Group and organizes symposia on Polymer Colloids.


Most significant recently published papers:


  • Patsula V., Kosinová L., Lovrić M., Ferhatovic L., Rabyk M., Konefal R., Paruzel A., Šlouf M., Herynek V., Gajovič S., Horák D., Superparamagnetic Fe3O4 nanoparticles: Synthesis by thermal decomposition of iron(III) glucuronate and application in magnetic resonance imaging, ACS Appl. Mater. Interfaces 23, 7238-47 (2016).
  • Zasonská B., Čadková M., Kovářová A., Bílková Z., Korecká L., Horák D., Thionin-modified poly(glycidyl methacrylate) nanospheres as label of antibodies for biosensing applications, ACS Appl. Mater. Interfaces 7, 24926–24931 (2015).
  • Kostiv U., Janoušková O., Šlouf M., Kotov N., Engstová H., Smolková K., Ježek P., Horák D., Silica-modified monodisperse hexagonal lanthanide nanocrystals: Synthesis and biological properties, Nanoscale 7, 18096-18104 (2015).
  • Horák D., Plichta Z., Starykovych M., Myronovskij S., Kit Y., Chopyak V., Stoika R., Calf thymus histone-conjugated magnetic poly(2-oxoethyl methacrylate) microspheres for affinity isolation of anti-histone IgGs from blood serum of patients with systemic lupus erythematosus, RSC Advances 5, 63050-63055 (2015).
  • Kostiv U., Šlouf M., Macková H., Zhigunov A., Engstová H., Smolková K., Ježek P., Horák D., Silica-coated upconversion lanthanide nanoparticles: The effect of crystal design on morphology, structure and optical properties, Beilstein J. Nanotechnol. 6, 2290–2299 (2015).
  • Koubková J., Macková H., Proks V., Trchová M., Brus J., Horák D., RAFT of sulfobetaine for modification of poly(glycidyl methacrylate) microspheres to reduce nonspecific protein adsorption, J. Polym. Sci. A: Polym. Chem. 53, 2273–2284 (2015).
  • Morales-Narváez E., Golmohammadi H., Naghdi T., Yousefi H., Kostiv U., Horák D., Pourreza N., Merkoçi A., Nanopaper as an optical sensing platform, ACS Nano 9, 7296–7305 (2015).
  • de la Escosura-Muñiz A., Plichta Z., Horák D., Merkoçi A., Alzheimer’s disease biomarkers detection in human samples by efficient capturing through porous magnetic microspheres and labelling with electrocatalytic gold nanoparticles, Biosens. Bioelectron. 67, 162–169 (2015).


COST Action CM1403 (2014-2018)

Chair: dr Hans Gorris (University of Regensburg, Germany)

Vice-Chair: prof.Tero Soukka (University of Turku, Finland)

COST Science Officer: Dr. Lucia Forzi (Bruseels, Belgium)

STSMs Manager: dr hab. Artur Bednarkiewicz (PAS & WCB EIT+, Poland)


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