Hans Heiner Gorris (DE)


Institute of Analytical Chemistry, Chemo- and Biosensors

University of Regensburg

93040 Regensburg



Phone : +49-941-9434015

Email : hans-heiner.gorris@ur.de


Academic studies and career

  • 1994 – 2001 Diploma in Biology, University of Münster (Germany) and University of York (England)
  • 2001 – 2005 PhD, University of Lübeck (Germany)
  • 2006 – 2009 Postdoctoral Fellow, Department of Chemistry, Tufts University, Medford (USA)
  • since 2009 Assistant Professor at the Institute of Analytical Chemistry, Chemo- und Biosensors, University of Regensburg (Germany); habilitation in 2015
  • since 2016 Heisenberg-Fellow of the German Research Council (DFG)

Research focus

  1. Upconverting nanoparticles: Background-free luminescent labeling for bioassays and bioimaging; ratiometric encoding strategies.
  2. Femtoliter Arrays: Single molecule analysis of enzyme kinetics; multiplexed assays.

Awards and memberships

  1. Heisenberg Fellowship of the German Research Council (2016-2018).
  2. Chair of the “European Upconversion Network” (COST Action CM1403)

Most significant publications


  1. Sedlmeier A, Hlaváček A, Birner L, Mickert MJ, Muhr V, Hirsch T, Corstjens PLAM, Tanke HJ, Soukka T, Gorris HH (2016): Highly sensitive laser scanning of photon-upconverting nanoparticles on a macroscopic scale. Anal. Chem. ahead of print, doi: 10.1021/acs.analchem.5b04147
  2. Sedlmeier A, Gorris HH (2015): Surface modification and characterization of photon-upconverting nanoparticles for bioanalytical applications. Chem. Soc. Rev. 44, 1526-1560.
  3. Hlaváček A, Sedlmeier A, Skládal, P, Gorris HH (2014): Electrophoretic characterization and purification of silica-coated photon-upconverting nanoparticles and their bioconju-gates. ACS Appl. Mater. Interfaces 6, 6930-6935.
  4. Gorris HH, Wolfbeis OS (2011): Photon-Upconverting Nanoparticles for Optical Encoding and Multiplexing of Cells, Biomolecules, and Microspheres. Angew. Chem. In. Ed. 52, 3584-3600
  5. Gorris HH, Ali R, Saleh SM, Wolfbeis OS (2011): Tuning the dual emission of photon-upconverting nanoparticles for ratiometric multiplexed encoding. Adv. Mater. 23, 1652-1655.

Further research

  1. Liebherr RB, Renner M, Gorris HH (2014): A single molecule perspective on the functional diversity of in vitro-evolved β-glucuronidase. JACS 136, 5949-5955.
  2. Gorris HH, Walt DR (2009): Mechanistic aspects of horseradish peroxidase elucidated through single-molecule studies. JACS 131, 6277-6282.
  3. Gorris HH, Rissin DM, Walt DR (2007): Stochastic inhibitor release and binding from single-enzyme molecules. PNAS 104, 17680-17685.


COST Action CM1403 (2014-2018)

Chair: dr Hans Gorris (University of Regensburg, Germany)

Vice-Chair: prof.Tero Soukka (University of Turku, Finland)

COST Science Officer: Dr. Lucia Forzi (Bruseels, Belgium)

STSMs Manager: dr hab. Artur Bednarkiewicz (PAS & WCB EIT+, Poland)


info @ ucnp.eu


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